Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1999-11-29
2000-12-12
Fay, Zohreh
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514912, A61K 3800
Patent
active
061599301
ABSTRACT:
The present invention provides a pharmaceutical composition for treatment of corneal and conjunctival lesion, and dry eye comprising albumin as an active ingredient. The pharmaceutical composition is also useful for increase of eye surface epithelium mucin secretion. The present invention further provides a method for treatment of corneal and conjunctival lesion and dry eye, which comprises administering, to a subject in need of such treatment, albumin in an amount effective. In addition, the present invention provides a use of albumin for manufacture of a pharmaceutical composition of the present invention.
REFERENCES:
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Database Drugu, AN 84-16297. Koning et al. Combination Therapy for Dendritic Keratitis with Acyclovir and Alpha--Interferon. Arch. Ophthalmol. 101(12), 1866-68 (Dec. 1983).
Gupta et al. Trypsin and Serum Albumin in Tear Fluids in Acute Adenovirus Conjunctivitis. BR. J. Ophthalmol 72(5), 390-393 (May 1988).
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Zavaro et al. Proteins in Tears from Healthy and Diseased Eyes. Symposium on Uveal Melanomes, Nov. 24, 1979. Doc Ophthalmol 50(1) (Recd. 1981). 185-199 (Jan. 1981).
Ran S et al. Topical Plasma Fibronectin Compared to Albumin and Saline for Wond Healing of Denervated Ophthalmology, Sarasotata, Florida, USA, Apr. 3. (Mar. 1989).
Fay Zohreh
R-Tech Ueno Ltd.
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