Synthesis of N-(2-hydroxyethyl)piperazine

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D29508

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active

043384439

ABSTRACT:
N-(2-hydroxyethyl)piperazine is prepared by carrying out a reductive alkylation and cyclization reaction of monoethanolamine and diethanolamine in presence of a hydrogen atmosphere and a hydrogenation-dehydrogenation catalyst.

REFERENCES:
patent: 2636033 (1953-04-01), Malkemas
patent: 2910477 (1959-10-01), Long, Jr.
patent: 3037023 (1962-05-01), Moss et al.
patent: 3383417 (1968-05-01), Lichtenwalter
Elderfield, "Heterocyclic Compounds", vol. 6, (1960), p. 429.

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