Intermediates for preparing HMG-CoA reductase inhibitors

Details Intermediates for preparing HMG-CoA reductase inhibitors Intermediates for preparing HMG-CoA reductase inhibitors

1987-06-22

1989-01-03

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 584, 544 70, 544148, 544149, 544158, 544159, 544163, 544171, 544230, 544374, 544391, 546 15, 546206, 548407, 548517, 548540, 549264, 549292, 549330, 549347, 549375, 549454, 558276, C07D30930, C07D29518

Patent

active

047958111

ABSTRACT:
A process for converting 6-carboxy to 6-hydroxymethyl mevinolin analogs and novel intermediates formed in this process are disclosed.

REFERENCES:
H. Staab, Angew. Chem. Internat. Edit., 1, 351, (1962).
K. Ishizumi, et al., Chem. Pharm. Bull., 16(3), 492, (1968).
Hajos, Complex Metal Hydrides, Elsevier Scientific Publishers, New York, 1979, pp. 49-55 and 333-337.

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