Novel carboxylic acids, benzoyl phenyl alkanoic acids and use th

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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562426, 560 9, 560 52, 260399, 2604055, 260410, 260413, 260465K, 260465G, 2605011, 26050115, 260544D, 260544S, 424308, 424317, C07C 5984

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043373534

ABSTRACT:
Novel carboxylic acids of the formula ##STR1## wherein Z is an aliphatic hydrocarbon chain selected from the group consisting of --(CH.sub.2).sub.n -- and --CH.dbd.CH--(CH.sub.2).sub.n-2 -- where the double bond may be at any point in the chain, n is an integer from 5 to 10 and X, X.sub.1, X.sub.2 and X.sub.3 are individually selected from the group consisting of hydrogen, halogen, alkyl of 1 to 5 carbon atoms, alkoxy of 1 to 5 carbon atoms, alkylthio of 1 to 5 carbon atoms, CF.sub.3 --, CF.sub.3 O-- and CF.sub.3 S-- and their non-toxic, pharmaceutically acceptable organic and inorganic salts and esters having analgesic and anti-inflammatory activity and their preparation.

REFERENCES:
patent: 3657430 (1972-04-01), Shen et al.
patent: 3828093 (1974-08-01), Bays et al.
patent: 3898275 (1975-08-01), Houlihan
patent: 3931286 (1976-01-01), Meier et al.
patent: 3931302 (1976-01-01), Allais et al.
patent: 4027040 (1977-05-01), Deraedt et al.

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