Pyrazolo[1,5-c]quinazoline derivatives and related compounds

Details Pyrazolo[1,5-c]quinazoline derivatives and related compounds Pyrazolo[1,5-c]quinazoline derivatives and related compounds

1978-07-19

1982-06-29

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4242485, 42424857, 544115, 544250, 548373, 548378, 548483, A61K 31505, C07D48704

Patent

active

043372554

ABSTRACT:
Compounds are provided having the structure ##STR1## wherein R.sup.1 is hydrogen, alkyl of 1-3 carbons, phenyl optionally substituted by R.sup.4 ; R.sup.2 is cyano; ##STR2## (wherein Z is a single bond or ##STR3## X is O or S); ##STR4## (wherein R.sup.9 is hydrogen or alkyl, Q is CH or N); ##STR5## wherein R.sup.6 is amino, alkylamino, dialkylamino, haloalkyl or ##STR6## and R.sup.4 and R.sup.5 are the same or different and represent hydrogen, lower alkyl, lower alkoxy, alkanoyloxy, benzyloxy, substituted benzyloxy, hydroxy, halogen (Cl, Br and F), nitro and trifluoromethyl; and R.sup.7, R.sup.8, m and n are as defined hereinafter. The above compounds are useful as anti-allergy agents.

REFERENCES:
patent: 3895027 (1975-07-01), Katner
patent: 3897434 (1975-07-01), Katner
patent: 3903106 (1975-09-01), Katner et al.
patent: 4083980 (1978-04-01), Schromm et al.

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