Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-02-28
1994-08-09
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
A61K 3155
Patent
active
053366751
ABSTRACT:
Mania is treated by administering, to a patient in need thereof, galanthamine or a salt or derivative thereof or a functional equivalent of galanthamine, the functional equivalent being an acetylcholinesterase inhibitor which is active substantially selectively at nicotinic receptor sites.
REFERENCES:
Gilman, et al., Goodman and Gillman's, The Pharmacological Basis of Therapeutics, pp. 150-158 and 238-241 (1990).
Bretagne and Valetta, Anesth. Analges. 22, pp. 285-292 (1965).
Thomsen & Kewitz, "Pharmacological Interventions on Central Cholinergic Mechanisms in Senile Dementia", (1989).
Vander et al., "Human Physiology", pp. 184-185 (1985).
"Martindale," pp. 1118-1119 (1992).
Heller-Brown, "Atropine, Scopolamine, and Related Antimuscarinic Drugs", 8:150-158 (1989).
Bech P. et al., Mania Scale (MAS), Scoring instructions and glossary of definitions, 1986, Acta. Psych. Scan. suppl., pp. 29-31.
Risch et al., Differential Mood Effects of Arecoline in Depressed Patients and Normal Volunteers, 1983, Psychopharmacology Bulletin, vol. 19, No. 4, pp. 696-698.
Davis K. L. et al., Physostigmine in Mania, 1978, Arch Gen Psychiatry, vol. 35, pp. 119-122.
Janowsky D. S. et al., Role of Acetylcholine Mechanisms in the Affective Disorders, 1987, Psychopharmacology: The Third Generation of Progress, ed. Herbert Y. Meltzer, Raven Press, New York, pp. 527-533.
Janowsky D. S. et al., Cholinomimetic and Anticholinergic Drugs Used to Investigate an Acetylcholine Hypothesis of Affective Disorders and Stress, 1984, Drug Development Research, vol. 4, pp. 125-142.
Fritze, J. et al., Erythrocyte Acetylcholinesterase in Psychiatric Disorders and Controls, 1987, Biol Psychiatry, vol. 22, pp. 1097-1106.
Proskurnina et al., J. Gen. Chem. 22, 1988-1902, Chemical Abstract, 47, 6959, (1953).
Paskow, "New Neuromuscular Blocking Agents", Hdbk, Exp. Pharmac. y, 653-672, (1986), p. 4.
Bretagne and Valletta, Anesth. Analges. 22, 285-292, (1965), p. 4.
Wislicki, Brit. J. Anaesth. 39, 963, (1967), referred to at p. 4, line 26.
Cozanitis et al, Der Anaesthesist, 416-421, (1971), referred to at p. 4, line 27.
Thomsen and Kewitz, Life Sciences, 46, 1553-1558, (1990), referred to at p. 4, line 30.
Thomsen and Kewitz, Dementia, 1990, 46-51.
Welner, et al., Extract from Psykiatri (1985) p. 1.
"Martindale," pp. 1332-1335 (1992).
Janowsky et al, Lancet, 2, pp. 632-635 (1972).
Merck Index, 11th ed., 1989, #4245.
Cintins Marianne M.
Jordan Kimberly R.
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