Process for producing octahydrocoumarins and same as a product o

Details Process for producing octahydrocoumarins and same as a product o Process for producing octahydrocoumarins and same as a product o

1996-07-17

1997-06-17

McKane, Joseph

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31106

Patent

active

056398930

ABSTRACT:
The present invention involves the production of octahydrocoumarins from coumarins and/or 3,4-dihydrocoumarins in good yields by a simple process which can be industrially carried out, by reducing coumarins and/or 3,4-dihydrocoumarins to octohydrocoumarins with hydrogen in the presence of an alcohol and a ruthenium catalyst, and optionally heating resultant 3-(2-hydroxycyclohexyl) propionate contained in the reduction reaction mixture to conduct cyclization/dealcoholization and convert same to octohydrocoumarins.

REFERENCES:
patent: 3859311 (1975-01-01), Symon et al.
patent: 3891678 (1975-06-01), Verheijen et al.
patent: 3936473 (1976-02-01), Symon et al.
patent: 3998851 (1976-12-01), Reichenbacher et al.
patent: 5218129 (1993-06-01), Shirafuji et al.
CA 98:197945 Synthesis and . . . benzopyran--2-one. Sanghvi et al., 1983.
CA 99:194466 Synthesis of . . . mevalonic acid. Carganico et al., 1983.
The Journal of the American Chemical Society, vol. 62 p. 3067 (1940).
The Journal of the American Chemical Society, Vo. 62, p. 283 (1940).
Journal of the Chemical Society, Perkin Transaction, II p. 431 (1988).
Journal of the Pharmaceutical Society of Japan, 74, p. 895 (1956).
Patent Abstracts of Japan, vol. 10, No. 28 (C-236) [2085], Feb. 4, 1986 and JP-A-60 181082 (Sumitomo Kagaku Kogyo K.K. Sep. 14, 1985.
De Benneville et al., "The Hydrogenation of Coumarin and Related Compounds," Journal of the American Chemical Society, vol. 62, 1940, Columbus, Ohio, pp. 283-287.

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