Difluoro antivirals and intermediate therefor

Details Difluoro antivirals and intermediate therefor Difluoro antivirals and intermediate therefor

1984-12-04

1987-09-08

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 23, 536 184, 536 26, 549454, A61K 3170, C07H 1700

Patent

active

046924345

ABSTRACT:
A 2,2-difluoro-2-desoxycarbohydrate is used to prepare antiviral nucleosides.

REFERENCES:
patent: 3282921 (1966-11-01), Verhegden et al.
patent: 3870700 (1975-03-01), Kotick et al.
patent: 4211773 (1980-07-01), Lopez et al.
patent: 4352795 (1982-10-01), Cook
DeClercq et al., Proc. Natl. Acad. Sci. USA 76, 2947-2951 (1979).
J. Med. Chem. 22, 21-24 (1979).
Howard J. Schaeffer, American Journal of Medicine, Jul. 1982, 4-6.
Kaufman and Heidelberger, Science 145, 585-586 (1964).
Prusoff, Biochim. Biophys. Acta 32, 295-296 (1959).
Witkowski et al., J. Med. Chem 15, 1150-1154 (1972).
De Rudder and De Garilhe, Antimicrobial Agents and Chemotherapy, 578-584 (1965).
Penglis, Advances in Carbohydrate Chemistry and Biochemistry 38, 195-285 (1981).
Fox et al., Seventh International Symposium of Medicinal Chemistry, 1980, published by Pergamon Press (1981), pp. 27-39.
Reichman et al., Carbohydrate Research 42, 233-249 (1975).
Wright and Taylor, Carbohydrate Research 6, 347-354 (1968).
Adamson et al., Carbohydrate Research 18, 345-347 (1971).
Hough et al., J. Chem. Soc. Perkin I, 784-788 (1972).
Masamune, Sharpless et al., J. Org. Chem. 47, 1373-1381 (1982).
Abstract, Spring 1983 ACS meeting at Seattle, D. E. Bergstrom.

Affiliated with

Also associated with

Rating

Difluoro antivirals and intermediate therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Difluoro antivirals and intermediate therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Difluoro antivirals and intermediate therefor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2158343