No synthetase inhibitors as medicinal products intended to reduc

Details No synthetase inhibitors as medicinal products intended to reduc No synthetase inhibitors as medicinal products intended to reduc

1995-07-27

1997-06-17

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 31195

Patent

active

056397925

ABSTRACT:
NO synthetase inhibitors intended to reduce the consumption of alcohol or to prevent excessive alcohol consumption in patients exhibiting an alcohol behavioral dependency are disclosed Among the cerebral NO synthetase inhibitors, L-nitroarginine may be particularly mentioned.

REFERENCES:
Adams et al., Alcoholism: Clinical and Experimental Research, vol. 19, pp. 195-199 (1995).
Rezvani et al., Pharmacology Biochemistry and Behavior, vol. 50: pp. 265-270 (1995).
Khanna et al., Brain Research Bulletin, vol. 32, pp. 43-47 (1993).
Kolesnikov et al., European Journal of Pharmacology, 221: 399-400 (1992).
Hunt et al., J. Hepalol., 14: 146-150 (1992).

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