Carbocyclic and heterocyclic fused-ring quinolinecarboxylic acid

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546 62, 546 61, 546 70, 546 64, 540577, 540578, 514215, 514284, 514287, 544184, 544216, 544233, 544247, 544343, C07D491048, C07D21502, C07D491052, A61K 3144

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056397593

ABSTRACT:
This invention relates to carbocyclic and heterocyclic fused-ring quinolinecarboxylic acid compounds, to pharmaceutical compositions comprising such compounds, and to methods of using such compounds for the treatment and/or prevention of organ transplantation rejection, graft versus host disease, autoimmune diseases, chronic inflammatory diseases, including but not limited to psoriasis and rheumatoid arthritis, and cancer in a mammal.

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