Substituted bridged-diazabicycloalkyl quinolone carboxylic acids

Details Substituted bridged-diazabicycloalkyl quinolone carboxylic acids Substituted bridged-diazabicycloalkyl quinolone carboxylic acids

1986-08-19

1988-10-04

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514215, 514216, 540473, 540582, 540583, C07D48704, A61K 3149

Patent

active

047756683

ABSTRACT:
Antibacterial compounds have the formula ##STR1## wherein R.sup.1 is hydrogen, a pharmaceutically aceptable cation, or alkyl; A is CH, CF, CCl or N; Y is alkyl, haloalkyl, cyclopropyl, vinyl, methoxy, N-methylamino, p-fluorophenyl, p-hydroxyphenyl or p-aminophenyl; or A is carbon and is taken together with Y and the carbon and nitrogen to which A and Y are attached to form a five to seven membered ring which is optionally substituted; and R.sup.2 is a bridged-diazabicycloalkyl group.

REFERENCES:
patent: 4146719 (1979-03-01), Irikura
patent: 4292317 (1981-09-01), Pesson
patent: 4382892 (1983-05-01), Hayakawa et al.
patent: 4448962 (1984-05-01), Irikura et al.
patent: 4499091 (1985-02-01), Wentland et al.
patent: 4571396 (1986-02-01), Hutt et al.

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