Combination therapy for treatment of female breast cancer

Details Combination therapy for treatment of female breast cancer Combination therapy for treatment of female breast cancer

1987-05-06

1988-10-04

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514800, 206219, A61K 3724, B65D 7704

Patent

active

047756616

ABSTRACT:
A method of treatment of breast cancer in susceptible animals whose ovarian hormonal secretions are blocked by surgical or chemical means, e.g., by use of an LH-RH agonist, e.g., [D-Trp.sup.6, des-Gly-NH.sub.2.sup.10 ]LH-RH ethylamide with a therapy comprising administering an antiandrogen, e.g., flutamide and an optionally, an inhibitor of adrenal sex steroid biosynthesis e.g., aminoglutethimide, pharmaceutical compositions useful for such treatment and two, four and five component pharmaceutical kits containing such compositions are disclosed.

REFERENCES:
patent: 4308347 (1981-12-01), Forrer et al.
patent: 4364474 (1982-12-01), Hollander, Jr.
patent: 4392492 (1983-07-01), Pick
patent: 4659695 (1987-04-01), Labrie

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