Methods for fine particle formation

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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12820023, 252305, 252314, 252319, 424 45, 424 46, 4272551, 4272556, A61K 4900, A61K 912, C09K 330, C23C 1600

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056394411

ABSTRACT:
Methods and apparatuses are provided for forming fine particles of a desired substance comprising dissolving said substance in a fluid such as water to form a solution and mixing the solution with a second fluid such as supercritical carbon dioxide which becomes a gas upon rapid pressure release, and with which the first fluid is at least partially immiscible, and releasing the pressure to form an air-borne dispersion or aerosol comprising particles having an average diameter between about 0.1 and about 6.5 .mu.m.

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