Thieno- and furopyrimidine-2,4-dione piperidine derivatives as s

Details Thieno- and furopyrimidine-2,4-dione piperidine derivatives as s Thieno- and furopyrimidine-2,4-dione piperidine derivatives as s

1988-03-15

1989-05-30

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544278, C07D49100, A61K 31505

Patent

active

048351571

ABSTRACT:
Novel thienopyrimidine-2,4-dione piperidine derivatives and novel furo[3,4-d]pyrimidine-2,4-dione piperidine derivatives are described. The novel piperidine derivatives are selective serotonin antagonists and alpha adrenergic blocking agents with cardiovascular, gastrointestinal and central nervous system activites.

REFERENCES:
patent: 4670560 (1987-06-01), Press et al.
patent: 4703120 (1987-10-01), Press
patent: 4707550 (1987-11-01), Press et al.
Kaplan, Arch. Intern. Med., vol. 143, 1983, pp. 255-259.
Royal Society of Medicine International Congress and Symposium Series, Rawlins et al., 1981, No. 41.
Buhler et al., Journal of Cardiovascular Pharmacology, vol. 7, Supplement 7, 1985.
Houston et al., Drugs, vol. 31, pp. 149-163, (1986).
Janssen, TIPS Reviews, 4, No. 198, 1983.
Janssen, Journal of Cardiovascular Pharmacology, No. 7, Suppl. 7, pp. 52-511, 1985.

Affiliated with

Also associated with

Rating

Thieno- and furopyrimidine-2,4-dione piperidine derivatives as s does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thieno- and furopyrimidine-2,4-dione piperidine derivatives as s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thieno- and furopyrimidine-2,4-dione piperidine derivatives as s will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2152773