Synthesis and immunogenicity of rotavirus genes using a baculovi

Details Synthesis and immunogenicity of rotavirus genes using a baculovi Synthesis and immunogenicity of rotavirus genes using a baculovi

1986-12-30

1993-02-16

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Lymphokine

530826, 4352351, 4351721, 4351723, 4353201, 935 24, 935 32, 935 57, 935 65, A61K 3912, C12N 700, C12N 1500

Patent

active

051869330

ABSTRACT:
A method to express rotavirus genes in a baculovirus system. Different clones are used to express rotavirus genes for all of the viral proteins. These proteins are isolated in their native conformation. Some of these proteins show antigenic properties and are used to vaccinate human, agricultural animals and pet animals against diarrheal disease. The antigenic proteins are also used to detect the presence of the viral infectious agent either by themselves or in conjunction with antibodies produced against the antigenic proteins.

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