Methods for the cultivation of infectious laryngotracheitis viru

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...

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435239, 4352402, 4242291, 424816, C12N 702, A61K 39245

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active

054439825

ABSTRACT:
This invention involves a chemically transformed chicken hepatocyte derived cell line which is capable of efficiently supporting replication of infectious laryngotracheitis virus (ILTV) and methods for cultivating ILTV using this hepatocellular carcinoma cell line. The virus harvested from these continuous cell culture methods can be used as a vaccine against ILTV infection.

REFERENCES:
patent: 3331736 (1967-07-01), Gelenczei
patent: 3444293 (1969-05-01), Hudson
patent: 4980162 (1990-12-01), Honda et al.
Condreay et al, "Efficient Duck Hepatitis B Virus Production by an Avian Liver Tumor Cell Line", Journal of Virology, vol. 64, Jul. 1990, pp. 3249-3258.
Kawaguchi et al, "Establishment and Characterization of a Chicken Hepatocellular Carcinoma Cell Line, LMH.sup.1 ", Cancer Research, vol. 47, Aug. 15, 1987, pp. 4460-4464.
Schnitzlein et al, Avian Diseases 38, 211, 1994.

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