Substituted 4-phenyl-pyridones and 4-phenyl-3-alkoxypyridines

Details Substituted 4-phenyl-pyridones and 4-phenyl-3-alkoxypyridines Substituted 4-phenyl-pyridones and 4-phenyl-3-alkoxypyridines

1993-12-14

1995-05-23

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 24, 546290, 514 89, A61K 3144, C07D21364

Patent

active

054182433

ABSTRACT:
Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines are prepared by reducing corresponding 4-phenyl-pyridone and 4-phenyl-2-alkoxypyridine derivatives. The substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines can be employed as active compounds in medicaments, in particular for the treatment of hyperlipoproteinaemia.

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J. Med. Chem., 1990, vol. 33, pp. 52-60; "Synthesis and Biological Activity of New HGM-CoA Reductase Inhibitors . . . ", G. Beck.

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