Water-dispersible granules

Plastic and nonmetallic article shaping or treating: processes – Spheroidizing or rounding of solid particles

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264140, 264141, 71 6408, B29B 900

Patent

active

054437644

ABSTRACT:
The invention relates to a process for the preparation of water-dispersible granules which comprises mixing the desired ingredients of the granules to form an extrudable composition, extruding the mixture, and rolling the extrusions to break them down into granules. The process of the invention is particularly suitable for the preparation of water-dispersible granules comprising agricultural chemicals (also known as dry flowables) as the process enables high production rates to be achieved and the products have high suspensibility and rapid dispersion.

REFERENCES:
patent: Re27214 (1971-11-01), Nakahara
patent: 3579719 (1971-05-01), Moriya
patent: 3627865 (1971-12-01), Wittwer
patent: 3758679 (1973-09-01), Seidler
patent: 3775331 (1973-11-01), Borrello
patent: 4036227 (1977-07-01), Zaffaroni et al.
patent: 4048268 (1977-09-01), Ludwig
patent: 4055618 (1977-10-01), Fujita
patent: 4082532 (1978-04-01), Imof
patent: 4665100 (1987-05-01), Ludwig
patent: 4845093 (1989-07-01), Haga et al.
Pesticide Formulations.
Adjuvants for Herbicides.
Advances in Pesticide Formulation Technology, 1984.
Pesticide Formulations & Application Systems 3rd Symp, 1982.
Pesiticide Formulations & Application Systems 4th Symp, 1983.
Dry Application of Dry Flowable Formulations WA, Grandrud et al.
WDG & WDG Technology, H. T. Delli Colli, Westvaco Corp.
MIMS Annual 1986, pp. 8-53.
Preparation of Small Solid Pharmaceutical Spheres, Conine et al, D&CI, Apr. 1970.
Effect of Processing Variables in Particles Obtained by Extrusion, Woodruff et al, J. Pharm Sci vol. 61, No. 5, May 1972.
Tablet-Granulations Composed of Spherical-shaped Particles, Jalal et al, J. Pharm Sci, vol. 61, No. 9, Sep. 1972.
The Characterisation of Wet Powder Masses Suitable for Extrusion/Spheronization, Harrison et al, J. Pharm Pharmacol. 1985.
Characterisation of the Sphericity of particles by the one Plane Critical Stability, Chapman et al, J. Pharm Pharmacol, 1988.
Converget Flow Analysis in the Extrusion of Wet Powder Masses, Harrison et al, J. Pharm Pharmacol., 1984.
New Technique for the Production of Spherical Particles, Manufacturing Chemist & Aerosol News, Jun. 1970.
Flow Detects in Wet Powder Mass Extrusion, Harrison et al, J. Pharm Pharmacol, 1985.
The Application of Capillary Rheometry to the Extrusion of Wet Powder Masses, Harrison et al, International J Pharmaceutics, 1987.
Thermal Studies on the Interaction of Water & Microcrystalline Cellulose., Fielden et al, J. Pharm. Pharmacol 1988.
Effect of Lactose Particle Size on the Extrusion Properties of Microcrystalline Celulose-Lactose Mixtures. Fielden et al, International J. Pharmaceutics, 1989.
The Influence of Lactose Particle Size on Spheronization of extrudate processed by a ram extruder. Fielden et al, J. Pharm Pharmacol, 1992.
A Comparison of the Extrusion & Spheronization Behaviour of Wet Powder Masses Processed by a Ram Extuder & a Cylinder Extruder. Fielden et al, Internat. J. Pharmaceutics 1992.
Antifungal Agents--Martindale The Extra Pharmacopoeia, 1989.
A Survey of Current Industrial Practices in the Formulation and manufacture of Tablets and Capsules Shangraw et al, Pharm. Tech. Jan. 1993.
Pharmaceutical Pelletization Technology, Ghebre-Sellassie, pp. 1-13, 217-227.
Extrusion & Spheronizing Equipment, Hicks et al, pp. 71, 86-87, 98-100.
Extrusion & Spheronizing Technology, O'Connor et al, pp. 187-192, 215-216.
Pharmaceutical Dosage Forms, vol. 3, 1990, pp. 35-39.
Effect of Spheronization Process Variables on Selected Tablet Properties, Malinowski et al, J. Pharm Sci, pp. 285-288, Feb. 1974.
Pellet Manufacture for Controlled Release Manufacturing Chemist, Jun. 1985.
Drug Development and Industrial Pharmacy 11(9&10) 1837, 1857 (1985).
Drug Development & Industrial Pharmacy 11(8) pp. 1523-1524 (1985).
Manufacture of Spherical Acetaminophen Pellets: Comparison of Torary Processing with Multiple-Step Extrusion and Spheronization Pharm Tech, May 1991.
Martindale: The Extra Pharmacopeia; Pesticides and Repellants pp. 1344, 1346, 1351.
Marumerizer, Luwa Corp.
The Theory & Practice of Industrial Pharmacy, Lachman et al, 1976, pp. 325-333, 337-339, 357, 628-630.
Modern Pharmaceutics, 2nd ed, pp. 360-363, 470, 475.
The Theory & Practice of Industrial Pharmacy, Lachman et al, 3rd ed, 1986, pp. 320-325, 692-694.
Remington's Pharmaceutical Sciences, 16th ed, pp. 1560-1565.
Influence of Extrusion-Spheronization Processing on the Physical Properties of D-Indobuffen Pellets Conaining pH Adjusters, Bianchini et al, Drug Delivery & Industrial Pharmacy 18(14) 1485 (1992).
Controlled Release of Bioactive Materials, Peppas et al, 1985.
Modern Pharmaceutics pp. 398-399.
Pharmaceutics: The Science of Dosage Form Design, Aulton, 1988, pp. 311-330.
Remington's Pharmaceutical Sciences, 1985, pp. 1610-1611.
Wet Granulation of Fine Powders, Luwa Corp.
Spartan Granulator, Luwa Corp.
Xtruder, Luwa Corp.

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