Sulfated oligosaccharides and derivatives thereof

Details Sulfated oligosaccharides and derivatives thereof Sulfated oligosaccharides and derivatives thereof

1989-09-27

1991-02-12

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 54, 536 175, 536 179, 536 176, 536 172, 536 22, C07G 300, C07H 1700, C07H 1900, C08B 3700

Patent

active

049925334

ABSTRACT:
The present invention relates to sulfated oligosaccharides or their derivatives such as the following compound and being useful for diagnosing or treating diseases such as immunity-related diseases and mucopolysaccharide diseases. ##STR1## (M is an alkali metal).

REFERENCES:
patent: 4415490 (1983-11-01), Joh
patent: 4607025 (1986-08-01), Petitou et al.
patent: 4675392 (1987-06-01), Dahmen et al.
patent: 4818816 (1989-04-01), Petitou et al.
Bo Nilsson et al., "Structure of Oligosaccharides and the Linkage Region Between Keratan Sulfate and the Core Proteoglycans from Monkey Cornea", Journal of Biological Chemistry, 258:10:6056-6063, 1983.
Peter Scudder et al., "Isolation and Characterization of Sulphated Oligosaccharides Released from Bovine Corneal Keratan Sulphate by the Action of Endo-.beta.-Galactosidase", Eur. J. Biochem., 157:365-373, 1986.
Maurice Petitou et al, "Synthesis of Heparin Fragments: A Methyl .alpha.-Pentaoside with High Affinity for Antithrombin III", Carbohydrate Research 167:67-75, 1987.

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