Process for the preparation of quinazoline-2,4-diones

Details Process for the preparation of quinazoline-2,4-diones Process for the preparation of quinazoline-2,4-diones

1998-05-26

1999-11-02

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D23972

Patent

active

059773626

ABSTRACT:
Quinazoline-2,4-diones are obtained in high yields and purities by reacting anthranilic acids with isocyanates and then, without isolation of the urea formed as intermediate, treating the reaction mixture with acid.

REFERENCES:
patent: 4287341 (1981-09-01), Hess et al.
patent: 4405623 (1983-09-01), Ishikawa et al.
patent: 4639518 (1987-01-01), Bandurco et al.
patent: 5539114 (1996-07-01), Cosmo et al.
A. Lespagnol, et al., "Derives de la benzoylene-uree(*)" Eur. J. Med. Chem., vol. 9, No. 3, pp. 263-268 (May-Jun. 1994).
Chemical Abstracts, vol. 83, p. 596, abstract No. 97348u, (1975).
E. Papadopoulos et al., "Convenient Preparation of N-Substituted 2-Amino-4H-3,1-benzoxazin-4-ones and 3-Substituted 2,4(1H,3H)-Quinazolinediones" J. Heterocyclic Chem., vol. 19, Mar./Apr. 1982, pp. 269-272.
J. Melendez, et al., "Synthesis of 3-Aryl-2,4-dioxo-1,2,3,4-tetrahydroquinazolines and 2-Arylamino-4-oxo-4H-3,1-benzoxazines from Methyl N-Aryldithiocarbamates", Synthesis, pp. 406-408 (1983).
Papadopoulos et al. J. Heterocyclic Chem., vol. 19, No. 269, pp. 269-272, 1982.

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