Prolactin production inhibitory agent

Details Prolactin production inhibitory agent Prolactin production inhibitory agent

1996-12-09

1999-11-02

MacMillan, Keith D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3147

Patent

active

059771321

ABSTRACT:
The prolactin production inhibition agent of the present invention containing a condensed cyclic compound, which is characterized by containing a condensed bicyclic structure of an optionally substituted homo or hetero 5- to 7-membered ring with an optionally substituted homo or hetero 5- to 7-membered ring, or a salt thereof, can be used, as a medicine, for the prophylaxis or therapy of diseases accompanied with an excess prolactin production or diseases having enhanced reactivity with prolactin, or is useful for inhibiting puerperal lactation, and also useful as a prophylactic or therapeutic agent of galactorrhea, hyperprolactinemic ovulation disturbance, amenorrhea-galactorrhea syndrome, prolactinoma, and besides, interbrain tumor, and acromegaly, pituitary gigantism.

REFERENCES:
patent: 3755372 (1973-08-01), Irmscher et al.
patent: 5744479 (1998-04-01), Furuya et al.
patent: 5807869 (1998-09-01), Furuya et al.
patent: 5817819 (1998-10-01), Furuya et al.
Sixteenth Edition--The Merck Manual of Diagnosis and Therapy, Berkow et al., 1992.
Stedman's Medical Dictionary, 26th Edition, pp. 57-58.
Endocrine Effects and Pharmacokinetic Characteristics of a Potent New Gonadotropin-Releasing Hormone Antagonist (Ganirelix) with Minimal Histamine-Releasing Properties: Studies in Postmenopausal Women; Jaron Rabinovici et al.,vol. 75. No. 5, pp. 1220-1225. Journal of Clinical Endocrinologoy and Metabolism, Acta Endocrinologica (Copenh) 1991, 124; 98-105.
Effects of a novel gonadotropin-releasing hormone antagonist (ORG 30850) on gonadotropin and prolactin secretion by rat pituitary cells in culture; Paul Franchimont et al.
Chemical Abstracts, "Thieno Compounds", vol. 106, (1987), p. 658.
R. Boehm et al., Pharmazie, vol. 41, (1986), H.9.
P. M. Gilis et al., "Synthesis and Antibacterial Evaluation of 4,7-dihydro-4-oxothieno[2,3-b]pyridine-5-carboxylic acids", Eur. J. Med. Chem. (1978), pp. 265-269.
N. Tamaki et al., Prolactine Producing Adenoma, Nihon Risho, vol. 51, No. 10, (1993), pp. 173-178.
Clinical Neuroscience, vol. 8, No. 4, (1990), pp. 74:428-77:431.{partial translation}.

Affiliated with

Also associated with

Rating

Prolactin production inhibitory agent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Prolactin production inhibitory agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prolactin production inhibitory agent will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2135841