Pharmaceutical composition comprising mirtazapine and one or mor

Details Pharmaceutical composition comprising mirtazapine and one or mor Pharmaceutical composition comprising mirtazapine and one or mor

1997-06-16

1999-11-02

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540578, A61K 3155, C07D48712

Patent

active

059770996

ABSTRACT:
The invention relates to a pharmaceutical composition comprising mirtazapine, a selective serotonin reuptake inhibitor (SSRI) and pharmaceutically acceptable auxiliaries. In particular the SSRI is selected from fluoxetine, fluvoxamine, citalopram, cericlamine, femoxetine, sertraline, paroxetine, ifoxetine, cyanodothiepin and litoxetine. The composition which can be used to treat depressant patients has less side effects than treatment of the patients with mirtazapine or the SSRI alone.

REFERENCES:
Davis et al., CNS Drugs, 5:5:389-402, May 1996.
Broekkamp, C.L.E. et al.: Prospects for improved Antidepressants. J. Med. Chem. vol. 38 (23), pp. 4615-4633, 1995.

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