Adjuvant for promoting absorption of pharmacologically active su

Details Adjuvant for promoting absorption of pharmacologically active su Adjuvant for promoting absorption of pharmacologically active su

1982-04-02

1984-11-27

Lovering, Richard D.

Compositions

Preservative agents

Anti-corrosion

424DIG15, 424271, 424365, 424178, 424179, 424170, 424172, 252 1, 252312, B01J 1300, A01N 6102, A61K 3120, A61K 4700

Patent

active

044850336

ABSTRACT:
Fatty acids having 8 to 14 carbon atoms, leucinic acid and nontoxic salts thereof promote the absorption of a pharmacologically-active substance through the rectum into the blood stream and effectively raise the concentration of such active substance in the blood stream even when said active substance is one which is usually absorbable through the rectum only with considerable difficulty.

REFERENCES:
patent: 2870201 (1959-01-01), Pollack
patent: 3262849 (1966-07-01), Lietz
patent: 4234450 (1980-11-01), Hirayama
patent: 4331653 (1982-05-01), Brown
patent: 4338306 (1982-07-01), Kitao et al.
Remington's Pharmaceutical Sciences, 14th ed., 1970, pp. 1617-1624.

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