Drug – bio-affecting and body treating compositions – Anti-perspirants or perspiration deodorants
Patent
1998-11-20
1999-11-02
Dodson, Shelley A.
Drug, bio-affecting and body treating compositions
Anti-perspirants or perspiration deodorants
424 66, 424 68, 424 7802, 424400, 424401, A61K 732, A61K 734, A61K 738, A61K 3174, A61K 700
Patent
active
059765143
ABSTRACT:
Disclosed are topical compositions which comprise from about 0.01% to about 60% by weight of an antiperspirant and/or deodorant active; from about 1% to about 60% by weight of a volatile, nonpolar hydrocarbon liquid having a solubility parameter of less than about 7.5 (cal/cm.sup.3).sup.0.5 and a vapor pressure as measured at 25.degree. C. of from about 0.01 mmHg to about 6.0 mmHg; and from about 1% to about 60% by weight of a skin irritation-mitigating material having a vapor pressure equal to or less than that of the volatile, nonpolar hydrocarbon liquid, preferably a silicone-containing liquid; wherein the weight ratio of the volatile, nonpolar hydrocarbon liquid to the mitigating material is from about 5:1 to about 1:50. It has been found that the volatile, nonpolar hydrocarbon liquid as defined herein can cause skin irritation when used in an antiperspirant or deodorant composition, even when used at relatively low concentrations, but that the skin irritation can be reduced or eliminated by the addition of a skin irritation-mitigating material, provided the material has the requisite vapor pressure and weight ratio relative to the volatile, nonpolar hydrocarbon liquid.
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Guskey Gerald John
Motley Curtis Bobby
Putman Christine Marie
Sawin Philip Andrew
Dodson Shelley A.
Hilton Michael E.
Procter & Gamble Company
Rosnell Tara M.
Winter William J.
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