Large dose pen

Details Large dose pen Large dose pen

1994-03-24

1997-05-06

Millin, Vincent

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604211, 222 47, 222309, 222390, A61M 500

Patent

active

056265662

DESCRIPTION:

BRIEF SUMMARY
CROSS REFERENCE TO RELATED APPLICATIONS

This application is a 35 USC 371 of PCT/DK92/00267 filed Sep. 7, 1992, the contents of which are incorporated herein by reference.
The invention relates to a pen shaped syringe for repetitive injection of individually set doses of a medicine from a reservoir in the syringe.
Such pen syringes are especially used by diabetics who have to inject themselves frequently with an insulin preparation to keep their blood glucose level within tolerable limits.
With the appearance of insulin preparations having a retarded action and of mixed preparations which make it possible to inject at the same time a preparation meeting an immediate need for insulin and a preparation covering the basic need for a long time, the time between injections is increased and so are the doses administered at each injection.
The doses are mainly set by rotating part of the pen syringe relatively to the rest of the syringe and numbers forming a scale along an edge of the one rotatable part of the syringe are moved in relation to an indicating mark on the rest of the syringe to indicate the set dose. Hereby the dose is limited by the fact that only a limited number of numbers can be placed along the edge of the rotatable part if they shall be readable at all. This problem is overcome by imparting the rotatable part an axial displacement concurrently with its rotation whereby instead of a circle a helical line becomes available for dose indicating numbers and even a scale covering rotation in excess of one turn.
The pen syringe should be as simple as possible to use, i.e. the normal use should only imply setting a dose and injecting the set dose, and both these steps should be simple to perform and this condition is met by most pen syringes. However, not all pen syringes offer the opportunity to cancel a set dose, so if a dose once set is not wanted for injection the only way to bring the syringe back in its neutral position is to spill the dose. With syringes by which large doses may be set this is not acceptable.
By a known type of syringe the scale is arranged along a helix having just one turn. A helical recess in a cylinder surface of a dose setting member is engaged by a pin on the syringe housing so that the dose setting member when rotated is axially displaced along its axis. After having been axially displaced by the setting of a dose, the dose setting member is pressed home to inject the dose. The engagement between the pin and the helical recess will cause a rotation of the dose setting member when it is axially pressed home, this rotation being in the opposite direction of the rotation for setting the dose. The rotation of the dose setting member is transferred to a screw
ut mechanism driving a piston in the syringe forward a distance proportional to the rotation.
The ends of the one turn helical recess are connected by an axial recess. This enables the setting member to be pressed axially back without imparting a rotary movement to this member if the rotary position of the member is so that the pin on the syringe housing engages the axial recess instead of the helical part of the recess. In this way a set dose may be cancelled by turning the dose setting member further until the pin engages the axial recess. However, this cancelling feature limits the effective dose setting rotation of the dose setting member to a little less than one turn, and further, as the demands for precision of the injected dose set a limit to the size of the dose per turning of the screw
ut mechanism, the size of the possible set dose is heavily restricted.
Consequently, it is the object of the invention to provide a pen syringe by which large doses may be set, a set dose may be cancelled, and the possibility of cancellation does not influence the possible size of a set dose or the simplicity of the normal use of the syringe.
This is obtained by a pen shaped syringe for repetitive injection of individually set doses of a medicine from a cylinder ampoule reservoir, comprising a dose setting member which may be ro

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patent: 5244465 (1993-09-01), Michel

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