L-pyranosyl nucleosides

Details L-pyranosyl nucleosides L-pyranosyl nucleosides

1996-10-02

1999-03-23

Wilson, James O.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 42, 514 43, 514 46, 514 47, 514 48, 514 49, 514 50, 514 51, 536 41, 536 172, 536 173, 536 181, 536 184, 536 2723, 536 276, 536 278, 536 2781, 536 281, 536 2853, 536 2854, A61K 3170

Patent

active

058859721

ABSTRACT:
This invention relates to .alpha. and .beta.-L-pyranosyl nucleosides of Formula (I), wherein the nucleoside substitution on the pyranosyl carbohydrate molecule comprises a substituted or unsubstituted purine (adenine or guanine) or pyrimidine (cytosine, uracil, thymine and hypoxanthine) base. Also provided are methods to make the .alpha. and .beta.-L-pyranosyl nucleosides and methods of using such to treat cancer in a mammal.

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