Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-03-26
1999-03-23
Robinson, Douglas W.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
514 12, 514 2, 530324, 536 236, 435419, 435423, 435424, 435425, 435426, 4352523, C12N 1509, C12N 1529, C12N 1582, C07K 1400
Patent
active
058858016
ABSTRACT:
Derivatives of .alpha.-hordothionin made by position-specific substitution with threonine residues provide threonine in plants.
REFERENCES:
patent: 5703049 (1997-12-01), Rao
Florack et al. Synthetic hordothionin genes as tools for bacterial disease resostance breeding. In: Agricultural Biotechnology in Focus in the Netherlands, Dekkers et al, eds. Pudoc, The Netherlands 1990.
Krebber et al. Expression of modified Seed storage proteins in transgenic plants. In:Transgenic Plants. Hiatt, ed. Marcel Dekker, Inc., New York. 1992.
Ponz et al. Cloning and nucleotide sequence of a cDNA encoding the precursor of the barley toxin .alpha.-hordothionin. Eur. J. Biochem. vol. 156, pp. 131-135. 1986.
Altenbach S.B. et al., "Manipulation of Methionine--Rich Protein Genes in Plant Seeds" Trends in Biotechnology, vol. 8, No. 6, 1990 pp. 156-160.
Altenbach S.B. et al., "Accumulation of a Brazil Nut Albumin in Seed of Transgenic Canola Results in Enhanced Level of Seed Protein Methionine", Plant Molecular Biology, 18: 235-245, 1992 pp. 235-245.
Anderson J. et al., "A Trasngenic Corn Line with Altered Levels of a High-Methionine Storage Protein", J. Cell Biochem Suppl., vol. 16F, p. 225, 1992, abstract.
Beach, L.R. et al., "Enhancing the nutritional value of Seed Crops", Current Top. Plant Physiol: Biosynthesis & Molecular Regulation of Amino Acids in Plants, vol. 7, 1992, pp. 229-238.
Florack, D.E.A et al., "Expression of biologically active hordothionin in tobacco, Effects of pre- and pro-sequences at the amino and carboxyl termini of the hordothionin precursor on mature protein expression and sorting", Plant Molecular Biology vol. 24 1994, pp. 83-96.
Garcia-Olmeda, F. et al. "Trypsin/alpha-amylase inhibitors and thionins from cereals: possible role in crop protection", Journal of Exp. Botany Supplement, vol. 42, No. 238, May 1991 p. 4 and abstract p. 1.5.
Gordon-Kamm et al. Transformation of Maize Cells and Regeneration of Fertile Transgenic Plants, 1990. The Plant Cell 2:603-618.
Karachi H. et al., "Seed Specific Expression of a Bacterial Desensitized Aspartate Kinase Increases the Production of Seed Threonine and Methionine in Transgenic Tobacco", The Plant Journal, vol. 3, No. 5, pp. 721-727, 1993.
Karachi H. et al., "Lysine synthesis and catabolism are coordinately regulated during tobacco seed development" PNAS 91, 1994 pp. 2577-2581, p. 2581 left col., last line of right col.
Maddox J. et al. "Cloning of a barley gene alpha-hordothionin, and expression in transgenic tobacco" J. Cell Biochem. Suppl. vol. 16F 1992 p. 217 and abstract p. 212.
Ohtari et al. 1991"Normal and lysine-containing zeins are unstable in transgenic tobacco" Plant Molecular Biol. 16:117-128.
Ozaki et al. 1980 "Amino Acid Sequence of a Purothionin Homolog from Barley Flour" J. Biochem 87.549-555.
Rao A.G. et al., "Validation of the Structure-function properties of alpha-hordothionin and derivatives through protein modeling"-see abstract; Protein Engineering: Supplement Advances in Gene Technology Protein Engineering and Beyond. Miami Winter symposium, Jan. 17-22, 1993 vol. 6.
Rao A.G. et al., "Structure-Function Validation of High Lysine Analogs of .alpha.-Hordothionin Designed by Protein Modeling", Protein Engineering, vol. 7, No. 12, pp. 1485-1493, Dec. 1994.
Reader's Digest "Success with House Plants" The Reader's Digest Association, Inc. 1979, pp. 459-461 Huxley et al. (eds).
Rodriguez-Palezuela et al. 1988 "Nucleotide sequence and endosperm-specific expression of the structural gene for the toxin .alpha.-hordothionin in barley" Gene 70: pp. 271-281.
Kimball Melissa L.
Pioneer Hi-Bred International , Inc.
Robinson Douglas W.
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