Hydrophobic agents and polymeric surfactants

Drug – bio-affecting and body treating compositions – Dentifrices

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Details

424 52, 424 53, 424 57, A61K 716, A61K 718, A61K 720

Patent

active

058855548

ABSTRACT:
Disclosed are oral compositions and methods for reducing plaque in a human or lower animal subject comprising applying to the teeth of the subject one or more hydrophobic solvents having one or more characteristics selected from the group consisting of a hydrogen bonding parameter of less than about 7.0 and a water solubility of less than about 10%; one or more polymeric surfactants wherein the weight ratio of hydrophobic solvent to polymeric surfactant is from about 10:1 to about 1:20; and one or more aqueous carriers; wherein the oral composition is in the form of a toothpaste or mouthrinse, is non-ingestible, and has a pH of from about 5.0 to about 9.5.

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