Process for the preparation of indolines

Details Process for the preparation of indolines Process for the preparation of indolines

1986-10-09

1989-12-12

Ceperley, Mary E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20908

Patent

active

048868876

ABSTRACT:
Indolines of the formula ##STR1## wherein R.sub.1 is hydrogen or C.sub.1 -C.sub.4 alkyl and each of R.sub.2 and R.sub.3 independently of the other is hydrogen, C.sub.1 -C.sub.4 alkyl or phenyl, are prepared by cyclodehydrating a 2-(2'-aminophenyl)ethanol of formula ##STR2## wherein R.sub.1, R.sub.2 and R.sub.3 are as defined above, at 150.degree.-350.degree. C. in the presence of an amorphous aluminum silicate.
The indolines of the above formula are useful intermediates for the synthesis of plant protective agents.

REFERENCES:
patent: 2283172 (1942-05-01), Bates
patent: 2283173 (1942-05-01), Bates
Ciba-Geigy, Derwent Abstract of European Patent 162,015, published Nov. 21, 1985.
J. Parera, Chem. Abstracts 85:192148(d) (1976).
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J. De Boer et al., Chem. Abstr. 72:115231e (1970).
F. Figueras Roca et al., Chem. Abstr. 70:109478h (1969).
Derwent and Japio Abstracts of Japanese Patents J 58-146563 (1983) and J 52-108969 (1977).
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F. Figueras Roca, L. DeMourgues and V. Trambouze, vol. 14, 107-113 (1969).

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