Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-07-30
1989-12-12
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544121, 544128, 544363, 546 19, 546115, 546157, 546158, A61K 3147, C07D40112
Patent
active
048868094
ABSTRACT:
Novel carbostyril derivatives and salts thereof having useful pharmacological activities such as myocardial contraction increasing activity (positive inotropic activity), coronary blood flow increasing activity, hypotensive activity, activity for inhibiting vasoconstriction induced by norepinephrine, and anti-inflammatory effect in one hand, while they do not possess activity for increasing heart beat at all substantially as well as show quite low toxicity and low side-effects in central nervous system activities.
REFERENCES:
patent: 4442107 (1984-04-01), Trijzelaar et al.
patent: 4791112 (1988-12-01), Bagley et al.
patent: 4792561 (1988-12-01), Walker et al.
Fujioka Takafumi
Kondo Kazumi
Ogawa Hidenori
Tamada Shigeharu
Teramoto Shuji
Otsuka Pharmaceutical Co. Ltd.
Raymond Richard L.
Turnipseed James H.
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