Isolation of HB.sub.s Ag

Details Isolation of HB.sub.s Ag Isolation of HB.sub.s Ag

1978-10-30

1980-01-01

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

260112B, 260112R, 195 14, 424 89, A61K 3900, A61K 3912, A61K 3942

Patent

active

041817133

ABSTRACT:
High purity HB.sub.s Ag is injected into guinea pigs to stimulate formulation of HB.sub.s Ab-positive serum. Gamma globulins containing HB.sub.s Ab are separated from the serum and the globulin fraction containing HB.sub.s Ab is isolated and coupled to a Sepharose gel. HB.sub.s Ag from HB.sub.s Ag-positive plasma is adsorbed on the gel by formation of an HB.sub.s Ab-HB.sub.s Ag complex. HB.sub.s Ag is eluted from the column and dialysed.

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