Certain nicotinamido-n-benzoic acid derivatives

Details Certain nicotinamido-n-benzoic acid derivatives Certain nicotinamido-n-benzoic acid derivatives

1978-02-16

1980-01-01

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546292, C07D21356, A61K 3144

Patent

active

041816587

ABSTRACT:
Benzoic acid derivatives of the formula ##STR1## wherein T is hydrogen or halogen, W is a carboxyl group, an ester or salt thereof; X is ##STR2## wherein R.sub.1 is alkyl having from 2 to 8 carbon atoms, aralkyl or phenyl, cycloalkyl, cycloalkylalkyl or alkylcycloalkyl; R.sub.2 is hydrogen or halogen, R.sub.3 is alkyl having from 5 to 8 carbon atoms, aralkyl or phenyl, or cycloalkyl having from 5 to 8 carbon atoms; R.sub.4 is hydrogen or alkyl; Y is a single chemical bond or a hydrocarbon chain having from 1 to 3 carbon atoms; and Z is hydrogen, halogen, alkyl, alkoxy, alkoxyalkoxy or alkenyloxy, have a blood sugar lowering effect and can be used for the treatment of Diabetes mellitus.

REFERENCES:
patent: 3879403 (1975-04-01), Kuhla et al.
patent: 4001259 (1977-01-01), Meyer et al.

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