Alkoxycarbonyl-ethylthio-azetidinones and process for their prep

Details Alkoxycarbonyl-ethylthio-azetidinones and process for their prep Alkoxycarbonyl-ethylthio-azetidinones and process for their prep

1976-03-24

1978-09-19

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260326S, 424244, 548301, C07D70508, A01N 31395

Patent

active

041153839

ABSTRACT:
2-Sulfinyl (or thio)-.alpha.-isopropenyl (or isopropylidene)-3-amido(or imido)-4-oxo-1-azetidineacetic acids and esters are prepared directly or indirectly from the reaction of a penicillin sulfoxide ester with an ester of acrylic acid. These compounds are active antimicrobial agents or are intermediates to active antimicrobial compounds.

REFERENCES:
patent: 3872086 (1975-03-01), Barton et al.
patent: 3900487 (1975-08-01), Underwood et al.
patent: 3920696 (1975-11-01), Kukdja et al.
patent: 3927013 (1975-12-01), Barton et al.
patent: 3953424 (1976-04-01), Barton et al.
patent: 3991069 (1976-11-01), Barton et al.
Ager et al., J.C.S. Chem. Comm., 1972, 601.
Bachi et al., J.C.S., Perkins I, p. 2326 (1972).
Soma et al., Chem. Abs., 82, 156034t (1975).

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