Cyclic anticoagulant peptides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 11, 514 14, 514 15, 514822, 530327, 530328, 530317, 930260, A61K 3702, C07K 706, C07K 708

Patent

active

051927454

ABSTRACT:
This invention relates to cyclic peptide derivatives which are useful anticoagulant agents.

REFERENCES:
patent: 4654302 (1987-03-01), Fritz et al.
patent: 4668662 (1987-05-01), Tripier
patent: 4767742 (1988-08-01), Dodt et al.
patent: 4791100 (1988-12-01), Krammer et al.
Rudinger, Peptide Hormones, Parsons (ed.), U. Park Press, Baltimore, pp. 1-7, (1976).
Hruby, Life Sciences, vol. 31, pp. 189-199 (1982).
Krstenansky et al., Biochim Biophys Acta, vol. 957, pp. 53-59 (Nov. 1988).
Mao et al, "Rapid purification and revised amino-terminal sequence of Hirudin: A specific thrombin inhibitor of the bloodsucking leech," Analytical Biochemistry, 161, 514-518 (1978).
Harvey et al, "Cloning and expression of a DNA coding for the anticoagulant hirudin from the bloodsucking leech, Hirudo medicinalis," Proc. Natl. Acad. Sci, U.S.A., vol. 83, pp. 1084-1088, Feb. 1986.
Krstenansky, J. L., et al., Thrombosis Research 54, 319-325 (1989).
Cram, D. J., et al., Organic Chemistry, 2nd Edition, McGraw Hill, p. 609 (1964).
Owen, T. J., et al., J. Med. Chem., 31, 1009-1011 (1988).
Minar, E., et al., Klin Wochenschr Feb 15;63(4):190-1 (1985) [abstract of].
Markwardt, F., et al., Thromb. Haemostasis, 52(2), 160-3 (1984) [abstract of].
Markwardt, F. et al., Thromb Haemost Jun 28:47(3):226-9 (1982) [abstract of].
Markwardt, F., et al., Thromb Haemost Jun 28:49(3):235-7 (1983) [abstract of].
Sturzebecher, The Thrombin (R. Machovich, Ed.) vol. 1, 131-160, CRC Press, Boca Roton, Fla. (1984).
Mao, S. J. T., et al., Biochemistry 27, 8170-8173 (1988).
Maraganore, J. M., et al., J. Biol. Chem. 264(15), 8692-8697 (1989).
S. Bajusz, et al., Peptides 32, 473 (1984).
Chemical Abstracts 52:2122 abstracting F. Markwardt, Z. Physiol. Chem. 308, 147-56 (1957).
J. Dodt, et al., FEBS Letters (165(2), 180-84 (1984).
Y-J. Chang, FEBS Letters 164(2), 307-13 (1983).
Derwent Ab. 86-162807/26. W. German Patent Appln. No. 3445532, published Jun. 19, 1986. C. Plantorgan, inventor.
Derwent Ab. 86-162802/26. W. German Patent Appln. No. 3445517, published Jun. 19, 1986, Gen-Bio Tec Ges Gen, assignee.
J. Dodt, et al., Biol. Chem. Hoppe-Seyler 366, 379-385 (1985).
D. Bagdy, et al., Methods Enzymol., 45 (Proteolytic Enzymes, Pt. B), pp. 674-675 (1976).
M. J. P. Pilat et al., Federatin Proc. 45(6), 1494, 76th Ann. Meeting, ASBC (Jun. 8-12, 1986.
J. L. Krstenansky, et al., FEBS Lett. 211(1) 11-16 (1987).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Cyclic anticoagulant peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclic anticoagulant peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclic anticoagulant peptides will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-211503

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.