Process for the production of indolyl lactic acid

Details Process for the production of indolyl lactic acid Process for the production of indolyl lactic acid

1974-09-13

1980-02-26

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603473, C07D30722, C07D209218

Patent

active

041905857

ABSTRACT:
A process for the production of indolyl lactic acid which includes heating an aqueous solution of 2,3-dihydro-2,5-furan dicarboxylic acid to boiling. The aqueous solution is cooled and reacted with phenyl hydrazine or a salt of phenyl hydrazine. The resultant phenylhydrazone is converted by heating with sulfuric acid to indolyl lactic acid.

REFERENCES:
Houlihan, "Indoles," Part 1, pp. 246-247 and 208-209 (1972).
Boberg et al., "Annalen Der Chemie", vol. 655, pp. 110-113 (1962).
Robinson et al., "Can. Jour. Chem.", vol. 35, pp. 1578-1581 (1957).
Robinson et al., "J. Chem. Soc.", 1932, p. 302.

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