Novel 9-substituted carbacyclin analogs

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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C07C 49559

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045902976

ABSTRACT:
Novel compounds of the following general formula: ##STR1##

REFERENCES:
patent: 4180657 (1979-12-01), Sih
patent: 4192891 (1980-03-01), Haslanger
patent: 4225507 (1980-09-01), Sih
patent: 4225508 (1980-09-01), Sih
patent: 4238414 (1980-12-01), Morton
patent: 4283575 (1981-08-01), Sih
patent: 4306075 (1981-12-01), Aristoff
patent: 4306076 (1981-12-01), Nelson
patent: 4420632 (1983-12-01), Aristoff
Aristoff, P. A., J. Org. Chem. 46 (No. 9), 1981, pp. 1954-1957, "Practical Synthesis of 6a-Carbaprostaglandin I.sub.2 ".
Barco, A., et al., J. Org. Chem. 45 (No. 23), 1980, pp. 4776-4778, "A New, Elegant Route to a Key Intermediate for the Synthesis of 9(O)-Methanoprostacyclin".
Hayashi, M., et al., Chem. Lett. 1979, pp. 1437-1440, "A Synthesis of 9(O)-Methanoprostacyclin".
Kojima, K., et al., Tetrahedron Lett. 39, 1978, pp. 3743-3746, "Total Synthesis of 9(O)-Methanoprostacyclin and Its Isomers".
Morton, D. R., Jr., et al., J. Org. Chem. 44 (No. 16), 1979, pp. 2880-2887, "Total Synthesis of 6a-Carbaprostaglandin I.sub.2 and Related Isomers".
Nicolaou, K. C., et al., J.C.S. Chem. Comm., 1978, pp. 1067-1068, "Total Synthesis of Carboprostacyclin, a Stable and Biologically Active Analogue of Prostacyclin(PGI.sub.2)".
Sugie, A., et al., Tetrahedron Lett. 28, 1979, pp. 2607-2610, "Stereocontrolled Approaches to 9(O)-Methanoprostacyclin".
Yamazaki, M., et al., Chem. Lett. 1981, pp. 1245-1248, "1,2-Carbonyl Transposition of cis-Bicyclo[3.3.0]octan-2-one to Its 3-one Skeleton: Application to Syntheses of dl-Hirsutic Acid and dl-9(O)-Methanoprostacyclin".
Shibasaki, M., et al., Chem. Lett. 1979, pp. 1299-1300, "A Stereo and Regiospecific Route to the Synthetic Intermediate for the Synthesis of 9(O)-Methanoprostacyclin".
Shibasaki, M., et al., Tetrahedron Lett. 5, 1979, pp. 433-436, "New Synthetic Routes to 9(O)-Methanoprostacyclin. A Highly Stable and Biologically Potent Analog of Prostacyclin".
Skuballa, W., et al., Angew. Chem. 93 (No. 12), 1981, pp. 1080-1081, "Ein neuer Weg zu 6a-Carbacyclinen--Synthese eines stabilen, biologisch potenten Prostacyclin-Analogons".
Mull und Abfall 12/78, p. 390.
Brennstoffchemie (Fritz Wirth) Wissenschaftliche und praktische Grundlage fur Chemie und Technik der Verbrennungsvorgange und der Brennstoffe) Berlin, Verlag von Georg Stilke 1922, p. 218.
Die Verwerting von Klarschlamm (W. Bischofsberger) Emschergenossenschaft, Essen, Umschau 1963, Heft 9, p. 281.
Thermische Verfahren zur Abfallbeseitigung (Lothar Barniske) der Landkreis 8-91977, p. 353-356.
CAV 1978, Oct., p. 126.
Wasser, Luft und Betrieb, 1962, Heft 12, p. 651.

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