Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544368, C07D41704, A61K 31495

Patent

active

045901961

ABSTRACT:
A series of non-opiate analgesics of Formula I ##STR1## wherein R.sup.1 is hydrogen, alkyl, aralkyl, or aryloxyalkyl; R.sup.2 is alkyl or hydrogen; and R.sup.3 and R.sup.4 are independently selected from hydrogen, alkyl, acyloxy, alkoxy, alkylthio, halogen, hydroxyl, or trifluoromethyl; or a pharmaceutically acceptable acid addition salt.

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patent: 4396770 (1983-08-01), Davis et al.
patent: 4411901 (1983-10-01), Temple et al.
patent: 4452799 (1984-06-01), Temple et al.
Chem. Abstracts, 71, (1969), 389541.
Chem. Abstracts, 61, (1964), 12008.

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