Platinum-flavin anti-tumor complexes

Details Platinum-flavin anti-tumor complexes Platinum-flavin anti-tumor complexes

1987-09-17

1989-01-10

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

A61K 31555, A61K 31675, A61K47514, C07F 965

Patent

active

047974850

ABSTRACT:
New platinum(II)-flavin complexes are now provided, which exhibit antitumor activities as shown by tests on mouse leukemia, L-1210 cells in mice. These novel platinum(II)-flavin complexes contain a 1,2-cyclohexanediamine, a 2-(aminomethyl)cyclohexylamine, an ethylenediamine or NH.sub.3 -- groups as a ligand or ligands.

REFERENCES:
Bowler, J. American Chemical Society 106, 6102 (1984).

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