Substituted benzene-fused hetero- and carbocyclics as nuerokinin

Details Substituted benzene-fused hetero- and carbocyclics as nuerokinin Substituted benzene-fused hetero- and carbocyclics as nuerokinin

1996-06-05

1997-11-25

Powers, Fiona T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514414, 514415, 514443, 5462774, 548454, 548467, 548503, 549503, A61K 3140, C07D20916, C07D20920, C07D33358

Patent

active

056913621

ABSTRACT:
Compounds represented by the structural formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein the variables are as defined in the specification; methods of treating asthma, cough, bronchospasm, inflammatory diseases, and gastrointestinal disorders with said compounds, and pharmaceutical compositions comprising said compounds are disclosed.

REFERENCES:
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Omura et al, Tetrahedron, 34 (1978), pp. 1651-1660.
Burkholder et al, Bioorganic Med. Chem. Let., 6, 8 (1996), pp. 951-956.

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