Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Patent
1996-02-07
1998-07-28
Mosley, Terressa
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
524801, 524837, A61K 690
Patent
active
057859779
ABSTRACT:
Non-metallic microparticulate carrier materials for a large and varied group of pharmaceutical and cosmetic agents are disclosed. Microdispersions of such carrier materials charged with at least one such pharmaceutical and/or cosmetic agent are also described. The microdispersions can be formulated for oral, parenteral, topical, inhalation and suppository administration. The formulations have varied uses depending on the pharmaceutical and or cosmetic agent utilized such as for combating microbial, fungal, yeast, viral and the like infections, treating acne, Herpes, burns, dermatoses caused by poisonous plants and irritants, reduction of wrinkles, moisturizing skin, etc. The microparticles are suitably charged particles of silica, alumina, boron, charcoal and the like and have a particle size of about 3 to about 250 .mu.m. The pharmaceutical and cosmetic active materials, which include ozone, vitamins, hormones, steroids, minerals humectants, etc., complex with the microparticles. The liquid carrier for the microparticles include water, propylene glycol, alcohols such as methanol, ethanol and propanols, and dimethyl sulfoxide. The resulting dispersions are believed to be similar to isotonic saline and mimic body fluids which makes the dispersions very physiologically compatible thereby aiding and speeding the delivery of the agents across membranes and to the afflicted tissue. Methods of using these microdispersions and the containing the same are also disclosed.
REFERENCES:
patent: 4824890 (1989-04-01), Glover et al.
patent: 4935464 (1990-06-01), Ona et al.
patent: 4999398 (1991-03-01), Gravier et al.
patent: 5371139 (1994-12-01), Yokoyama et al.
patent: 5504149 (1996-04-01), Kosal
patent: 5643555 (1997-07-01), Collin et al.
Mosley Terressa
Sommer Evelyn M.
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