Metalloproteinase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

5142382, 514507, 514541, 544169, 548127, 560 13, 560312, A61K 3141, C07D28506

Patent

active

061243299

ABSTRACT:
Compounds of general formula (II) ##STR1## wherein R.sub.1, R.sub.2 and Z are defined in the claims, are matrix metalloproteinase inhibitors.

REFERENCES:
patent: 4885027 (1989-12-01), Pomidor
patent: 5300501 (1994-04-01), Porter et al.
patent: 5310763 (1994-05-01), Campion et al.
patent: 5552419 (1996-09-01), MacPherson et al.
patent: 5817822 (1998-10-01), Nantermet et al.
patent: 5962529 (1999-10-01), Miller et al.

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