Senescent cell derived inhibitors of DNA synthesis

Details Senescent cell derived inhibitors of DNA synthesis Senescent cell derived inhibitors of DNA synthesis

1992-11-02

1994-04-12

Hill, Jr., Robert J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 234, 536 235, 435 4, 435 6, 435 691, 4351721, 4352402, 530350, C07H 1512, C07H 1700, C07K 300, C12P 2106

Patent

active

053027060

ABSTRACT:
An expression vector cDNA library derived from senescent cells has been used to isolate cDNA clones that encode inhibitors of DNA synthesis. Such inhibitors play a role in cellular senescence and aging. Antisense nucleic acids reduce the inhibition of DNA synthesis.

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