Pyrazolo(1,5-c)quinazoline derivatives and related compounds

Details Pyrazolo(1,5-c)quinazoline derivatives and related compounds Pyrazolo(1,5-c)quinazoline derivatives and related compounds

1977-03-17

1978-09-05

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544252, 548378, 260325R, C07D48704, A61K 31415, A61K 31505

Patent

active

041120965

ABSTRACT:
Compounds are provided having the structure ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different and R.sup.1 is hydrogen, alkyl of 1-3 carbons, phenyl optionally substituted by R.sup.4 or ##STR2## R.sup.2 is ##STR3## hydrogen, lower alkyl or phenyl optionally substituted by R.sup.4 with the proviso that at lest one of R.sup.1 and R.sup.2 is ##STR4## R.sup.3 is hydrogen, lower alkyl, benzyl or phenyl optionally substituted by R.sup.4 ; and R.sup.4 and R.sup.5 are the same or different and represent hydrogen, lower alkyl, lower alkoxy, alkanoyloxy, benzyloxy, hydroxy, halogen (C1, Br and F), nitro, and trifluoromethyl; R.sup.6 is hydrogen, lower alkyl, alkanoyl, aroyl, aralkanoyl, aralkyl or phenyl; and R.sup.7, R.sup.8, m and n are as defined hereinafter.
These compounds are useful as anti-allergics.

REFERENCES:
patent: 3171740 (1965-03-01), Menzel et al.
patent: 3313815 (1967-04-01), Wolfe et al.
patent: 3531482 (1970-09-01), Ott
patent: 3810894 (1974-05-01), Kranz et al.
patent: 3890324 (1975-06-01), Katner
patent: 3895027 (1975-07-01), Katner
patent: 3897434 (1975-07-01), Katner
patent: 3899508 (1975-08-01), Wikel
patent: 3903106 (1975-09-01), Wikel
patent: 4002755 (1977-01-01), Yamamoto et al.

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