Cyanomethylthioacetylcephalosporin intermediates

Details Cyanomethylthioacetylcephalosporin intermediates Cyanomethylthioacetylcephalosporin intermediates

1977-09-01

1978-09-05

Brust, Joseph Paul

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2604654, C07C12116, C07C12166

Patent

active

041119789

ABSTRACT:
New compounds of the following general formula, and their salts ##STR1## wherein R.sub.1 and R.sub.2 each is hydrogen, lower alkyl, lower alkenyl, phenyl, hydroxyphenyl, chlorophenyl, benzyl, phenethyl, or R.sub.1 and R.sub.2 together complete a cyclopentyl or cyclohexyl group; R.sub.3 is hydrogen, lower alkyl, lower alkenyl, cyclopentyl, cyclohexyl, phenyl, hydroxyphenyl, aminophenyl, chlorophenyl, benzyl, furyl, thienyl, pyrrolidyl or pyridyl; and R.sub.5 is hydrogen or lower alkyl; are intermediates for the production of cephalosporin derivatives.

REFERENCES:
patent: 1762719 (1930-06-01), Hoffa et al.
patent: 1803781 (1931-05-01), Wagner et al.
patent: 2900360 (1959-08-01), Schmitz-Josten
patent: 3069457 (1962-12-01), Lynn et al.
patent: 3137722 (1964-06-01), Toland, Jr.
patent: 3919208 (1975-11-01), Patchornik et al.

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