Thiazole and imidazole derivatives and antiulcer composition con

Details Thiazole and imidazole derivatives and antiulcer composition con Thiazole and imidazole derivatives and antiulcer composition con

1991-04-09

1992-12-15

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548166, 548169, 548171, 548173, 548174, A61K 31425, C07D27774, C07D27776

Patent

active

051717468

ABSTRACT:
A thiazole or imidazole derivative having the general formula (I): ##STR1## wherein: R.sup.1 and R.sup.2, which may be the same or different, each independently represent a hydrogen atom, or a phenyl or heteroaryl group, or R.sup.1 and R.sup.2 may together form a benzene ring which may be optionally substituted by a halogen atom or a lower alkyl optionally substituted by a halogen atom, lower alkoxy or nitro group;

REFERENCES:
patent: 2410407 (1946-11-01), Dusland
patent: 4451471 (1984-05-01), Ferrini et al.
patent: 4567267 (1986-01-01), Wei et al.
D'Amico, J. Heterocyclic Chem. 24, pp. 945-948 (1987).
Sanfilippo et al., J. Med. Chem. 31, pp. 1778-1785 (1988).

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