2-Amino-pyridyl nitromethylketones and 2-amino-phenyl nitromethy

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424330, 544 93, 544 94, 260296R, 260577, A61K 3144

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041171373

ABSTRACT:
2-Amino-3-pyridyl (or phenyl) nitromethylketones are prepared eg by reacting a 3,4-dihydro-1,3-dioxo-1H-pyrido [2,3-d][1,3]oxazine (a 3-azaisatoic anhydride) with the carbanion resulting from the reaction of nitromethane with a porton abstracting agent. The compounds are useful as anti-allergic agents.

REFERENCES:
seter, abst. no. 28479z, vol. 66 of Chemical Abstracts (1967) (Abst. of Seter, Israel J. Chem., vol. 4, pp. 7-22 (1966-unavailable to Examiner in charge).
Beckwith et al., Chem. Abstracts, vol. 70, abst. no. 11669w (1969) (abst. of Beckwith et al., J. Chem. Soc., C 1968, pp. 2756-2759).
Beckwith, Chem. Abstracts, vol. 74, abst. no. 76430p (1971) (abst. of Beckwith, Ger. Offen. 1,926,475).
Sandison et al., Chem. Abstracts, vol. 82, abst. 72911p (1975).
Alessandrini et al., J. Chem. Soc. Dalton Trans. 1973, pp. 2409-2413.

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