Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1977-07-06
1978-09-26
Randolph, John D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424330, 544 93, 544 94, 260296R, 260577, A61K 3144
Patent
active
041171373
ABSTRACT:
2-Amino-3-pyridyl (or phenyl) nitromethylketones are prepared eg by reacting a 3,4-dihydro-1,3-dioxo-1H-pyrido [2,3-d][1,3]oxazine (a 3-azaisatoic anhydride) with the carbanion resulting from the reaction of nitromethane with a porton abstracting agent. The compounds are useful as anti-allergic agents.
REFERENCES:
seter, abst. no. 28479z, vol. 66 of Chemical Abstracts (1967) (Abst. of Seter, Israel J. Chem., vol. 4, pp. 7-22 (1966-unavailable to Examiner in charge).
Beckwith et al., Chem. Abstracts, vol. 70, abst. no. 11669w (1969) (abst. of Beckwith et al., J. Chem. Soc., C 1968, pp. 2756-2759).
Beckwith, Chem. Abstracts, vol. 74, abst. no. 76430p (1971) (abst. of Beckwith, Ger. Offen. 1,926,475).
Sandison et al., Chem. Abstracts, vol. 82, abst. 72911p (1975).
Alessandrini et al., J. Chem. Soc. Dalton Trans. 1973, pp. 2409-2413.
Randolph John D.
Sandoz Inc.
Sharkin Gerald D.
Vila Richard E.
Weinfeldt Frederick H.
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