Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1986-08-27
1988-08-30
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530331, 530332, 424 88, C07K 508, A61K 3702
Patent
active
047677430
ABSTRACT:
Peptide components of formula 1, pharmaceutically acceptable base salts thereof, pharmaceutical compositions and their use as antiinfective agents ##STR1## where R.sub.1 is alkyl, cycloalkyl or cycloalkylmethyl; R.sub.2 is hydrogen or alkyl and R.sub.3 is hydroxy or an amino acid residu of the formula ##STR2## where X is hydrogen, alkyl or hydroxymethyl and n is an integer of 0 to 4 and R.sub.4 and R.sub.5 are alkyl, hydrogen, benzyl or cyclohexylmethyl.
REFERENCES:
patent: 4354966 (1982-10-01), Kitaura et al.
Chem. Abstr. vol. 93 No. 47159u, 1980 (Okada et al., Abstract of Koenshu-lyo Masu Kenkyu Kai vol. 3 pp. 249-255 1978).
Chem. Abstr. vol. 87, No. 147351v, 1977 (Okada et al., Abstract of Chem. Pharm. Bull. vol. 25(7), pp. 1497-1508, 1977).
Okada et al., Chem. Pharm. Bull. vol. 25(7) pp. 1497-1508 (1977).
Chan Christina
Frost Albert E.
McManus James M.
Pfizer Inc.
Phillips Delbert R.
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