Process for preparing 7-deoxysteffimycinol

Details Process for preparing 7-deoxysteffimycinol Process for preparing 7-deoxysteffimycinol

1977-11-16

1978-09-26

Tanenholtz, Alvin E.

Textiles: fiber preparation

195 96, C12D 920

Patent

active

041167694

ABSTRACT:
Bioconversion of the antibiotic steffimycinone to the antibiotic steffimycinol. Steffimycinol is active against various microorganisms, for example, Bacillus subtilis, Mycobacterium avium and Streptococcus pyogenes. Steffimycinol is converted to 7-deoxysteffimycinol by a microaerophilic Aeromonas hydrophila fermentation. 7-Deoxysteffimycinol is active against Sarcina lutea, Bacillus cereus, and B. subtilis. Thus, these antibiotics can be used to inhibit the growth of the above microorganisms in various environments.

REFERENCES:
patent: 3976667 (1976-08-01), Kelly
patent: 3987028 (1976-10-01), Lunel et al.
patent: 4013515 (1977-03-01), Florent et al.
Biochemistry, vol. 15, pp. 4139-4145 (1976).
The Journal of Antibiotics, vol. 28, No. 10, pp. 838-840 (Oct. 1975).

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