Morpholinyl derivatives of doxorubicin and process for their pre

Details Morpholinyl derivatives of doxorubicin and process for their pre Morpholinyl derivatives of doxorubicin and process for their pre

1993-01-13

1994-04-19

Lone, Werren B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568591, C07C 43313, C07C 4330

Patent

active

053046870

ABSTRACT:
Morpholinyl derivatives of doxorubicin having the general formula A: ##STR1## in which X represents a linear or branched C.sub.2 -C.sub.6 alkyl group or a benzyl group --CH.sub.2 C.sub.6 H.sub.5 and which have (S) or (R) configuration at carbon atom C-2" of the morpholino ring, are antitumor agents.

REFERENCES:
patent: 4374980 (1983-02-01), Umezawa et al.
patent: 4672057 (1987-06-01), Bargiotte et al.

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