Preparation of optically-active cyanomethyl esters

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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502167, B01J 3100

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active

046819479

ABSTRACT:
Optically-active alpha-cyano esters are prepared by treating a non-symmetrical ketene with a racemic or an optically-active alpha-hydroxynitrile or with an aldehyde and cyanide ions in the presence of an optically-active amine catalyst.

REFERENCES:
patent: 4086219 (1978-04-01), Wittle et al.
Chem. Abstr., vol. 102, (1985) 5947y and 112889c.
Oku et al., Makromol. Chem., 183, 579-586, (1982).
Oku et al., J.C.S. Chem. Comm., No. 5, 229-230, (1981).

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